I have many friends who are women, and a wife who is a woman, and none of them are significantly different for me to talk to than men. I don’t know what to tell you.

Sure there are cultural differences. Men are more likely to discuss some topics than women are, and vice versa. And there are stereotypical differences like women being more open with their feelings (though I’ve always been pretty open about my own as a man). We assign plenty of interests to specific genders, but there are always those who cross those lines.

I’ve always found that treating women essentially the same way I treat men has worked just fine.